Trigger is a piece of cake. Safety is easy.
Charging handle needs to be lefty or ambi, since you have to take the gun much further off your shoulder do and awkward motion with the left wrist to activate. Can't be done fast for 3-gun.
Have to move gun to right hand to lock bolt back. Shells and gas in your face. It's a pain. If I get back into it, it's going to be a lefty set up.
Odds were good the OP wasn't running 3-gun (even w/ explosive growth its still a TINY fraction of shooters.) Yes, If looking for every last fraction of a second running a gun designed for righties (cough, AR, cough) it going to be slower for a leftie. Its a lot easier now-a-days to pick a ambi platform than it was 10yrs ago. 3-gun will present its own challenges to a one-eyed shooter beyond the controls. You're going to have to shoot weak side around a barrier eventually. The race gun is going to have to have some sort of riser/offset so one could shoot either handed w/ the same eye. Im a rightie and can shoot 'ok' left handed w/ my left eye. No way I could use any existing rifle I have and shoot left handed w/ my right eye. ALL the sights are too low.