No point in shooting as much as the cylinder chamber will hold. Velocity gain is negligible and abusing the gun (especially if it's an open top Colt) in such a manner will wear it out/loosen it it a lot quicker than by shooting reduced charges. I have a Navy Arms .36 Colt Navy replica from the first year it was introduced- 1959- and it is as tight as the day it was made since it was only ever fired with low/sane powder charges. A buddy bought one somewhat newer than this one, and shot it a lot with heavy charges and it was ready for the trash can in less than 10 years.