Don't classify myself as a "fanboy", but this is easy, 6.5CM is the future all the way. Inherently accurate by design. Not to take away from any other cartridges in the neighborhood....they all obviously work, 243, 25-06, 257, 7-08.... but the only one that has a base even remotely close to the 6.5 now is 243. Check ammo availability (not what's available now, but what's available, period). No contest, there's a wide selection, from light to heavy, from every mfr. It's up there with 223 and 308. Oh, and I didn't get a passthrough on a sika with my 7mag one time, so now I won't go with anything less than a 378 wby