I think every collection should have at least one Ruger MK _?_ in it, and the newer ones certainly are optics ready. Were it not for your interest in optics, I would reccomend the Ruger SR22 for the wife and daughter to start out with. My wife has one (though it's not where she started). What's nice as a starter is that it has the same feel and controls as a centerfire DA/SA pistol (to me, the MK series feels more like a target pistol). Also, the SR22 fits her little hands perfectly, but my fat fingers can also handle it just fine.
There are soooo many options out there...but remember that your "first" doesn't have to be your "only"
There are soooo many options out there...but remember that your "first" doesn't have to be your "only"