engineerbrian
JMB fan club
I have killed deer with a 223 and 22-250 ( three total) but they are far from my first choices (22-250 is a lot better). I think your barrel being short will affect the outcome as well.
That said I have also guided a new hunter to their first deer (in Tennessee) with a NEF Handi-Rifle in 223 the shot wasn't seventy yards text book broad side shot. The deer piled up after 50 or so yards. The rifle was used because she shot it a great deal better than the 243.
All I can say is if you are going to do it with a short barrel do not make the shot past 100 yards. More important is to choose a good bullet that will hold together. For above deer and the two killed with a 22-250 the bullet was a 55grain Federal Trophy Bonded Bear Claw. I do not think the still make it but you may be able to find a box.
Both deer shot with 22-250 were about 100 yards and dropped immediately (both broad side). The 223 shot was at 70 yards (fired through a Bushmaster Varminter) that buck ran more than sixty yards and did not bleed much. Bullet was a Hornady 75 grain TAP another good choice.
All my barrels used were 22-24" and I think the longer barrel helped. Last advice is if you shoot them let them be (at least 45 minutes). This allows them to bleed out. A 22 hole can be plugged easy by leaves or mud when they lay down. That makes tracking very difficult.
You can do it with a 223 but are better served by borrowing a more suitable rifle. IMHO
I hunt with a guy that uses a 22-250 for deer, and let me tell you, it drops them is their tracks. Just as everyone else will say, shot placement and proper ammo is key.